Russian version of the coronavirus SARS-CoV-2
Scientists from the St. Petersburg Smorodintsev Institute of Influenza first sequenced the genome for the Russian variant of the SARS-CoV-2 coronavirus and found that, on the whole, it differs little from the original Chinese variants, but is genetically closest to European viruses.
A few days ago, the Influenza Institute announced that scientists received the first complete genome of the SARS-CoV-2 coronavirus from samples taken from a patient from Russia.
|Coronavirus was distinguished into two subtypes: the most common L (70%) and S (30%).|
According to Andrey Komissarov, RNA of the virus was isolated on March 15 in St. Petersburg from a nasopharyngeal smear taken from a thirty year old woman. It took a few more days to double-check and "reassemble" the genome: colleagues from the Center for Bioinformatics and Algorithmic Biotechnology of St. Petersburg State University helped.
"We found five non-synonymous replacements in the genome compared to the Chinese variant, this is quite a bit," said Komissarov. In his opinion, it is unlikely that the differences found will be able to change the virus so seriously that it will require a change in approaches to vaccine development.
- The scientists intend to create a Russian consortium for sequencing viruses SARS-CoV-2 and invite other scientific organizations working in the field of NGS to participate.
By his genetic characteristics, he says , the Russian virus "is located inside a large, predominantly European treasure, with a large number of basal European sequences." Komissarov also confirmed his words: "Yes, he is grouping with the European sequences.